How can I get the ioncube loaders working with GoDaddy?

Set up a file called: php5.ini

In it put this line:

zend_extension=/home/content/m/a/r/yourlogin/html/ioncube/lin_x86/ioncube_loader_lin_5.2.so

This should be the full path to ioncube loaders.  If you don't know the full path, run this script in the ioncube area:

http://www.yoursite.com/ioncube/ioncube-loader-helper.php

Try reloading your encoded file and see if that works.